Technical Capabilities

SOLID DOSAGE FORMS

Our facility includes state-of-the-art equipment :

Wet granulation

Integrated Granulation Lines 600 (Aeromatic Fielder PMA 600) and 1200 (Glatt Powrex 1200)
– Wet granulation & Fluid Bed Drying (including ethanol and nitrogen )
– Dry Granulation/Alexanderwerk WP 50 N75 (Roller compactor)

Drying

– Aeromatic TSG 6
– Glatt WG1200

Milling

– Cone Mill Rubitec
– Frewitt MG 803

Lubrification – Blending

– CMS Bin Blender

Tableting

5 compression suites:

– 3 triple layer presses – Elizabeth Hata
– 1 Fette P 2100,
– 1 Kilian Presscoater S 250

Film coating

– Glatt GCM 350

Capsule filling

– Macofar Romaco (powder and tabs in capsule)

ENHANCED BIOAVAILABILITY
  • High pressure homogenizer equipment from Microfluidics → particle size reduction under pressured water
  • Connected with Fluid Bed Dryer for top spray granulation

Maintenance

Our Energy and Fluids system :

WATER

4 purified water system for Production area:

• P04: 500l/h for Microfluidization part (ELGA-VEOLIA)

• P05: 1500l/h (PERMO CHRIST)

• P06: 1000l/h for others Production area (PERMO CHRIST)

• P07: 10l/h for a cleaning area (ELGA-VEOLIA)

1 purified water system for Pilot Plan:

• P03: 130l/h (ELGA-VEOLIA)

1 main demineralised production for QC Laboratory area (ELECT 50)

HVAC

• 31 AHUS for 56.692 m3 with Air Treatment

AIR

• Compare D50H RS free oil with water injection Class 0 ISO 8573-1

• Atlas Copco oil free 700 Nm³/h in back up

• Antares dyer ATT140 (dew point -80°C)

STEAM

• 2 systems – 3.000kg/hour each (Brand: STEIN)

• 1 system – back up currently turned off – 1.000 kg/h (Brand: STEIN)

4 Systems : clean steam

SECURITY

• Site monitored 24/7 by an external company, equipped with cameras and card readers

• Fire protection: water

• CTM (centralized technical management) and BMS (building management system) for Critical equipment